Although cancer cells derived from normal tissues, the changes made to acquire malignant potential should be sufficient for the immune system was able to recognize and destroy. In fact many early tumors are destroyed by the immune system before they kill to be developed. On the other hand the fact that despite the agency's efforts to stop cancer development, it involves both end up producing the immune system fails to recognize their work altearciones that lead to cancer and that cancer cells activate mechanisms to evade the immune response. In the laboratory of Dr. Irvine explore the relationship between cancer and immune system in animal models human tissues and to try to understand why the immune system fails to create therapeutic antibodies through protein engineering stuck. ( http://ki.mit.edu/research/immune )
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